Medication Doses

Acetaminophen and Ibuprofen Questions and Answers

Acetaminophen (used in Tylenol) and ibuprofen (used in Advil and Motrin) are medications used to treat fever and pain. Here are answers to some common questions about fever, and how acetaminophen and ibuprofen can be used to manage your child’s symptoms.

  • Fever is our body’s normal response to infections and is a very common symptom of childhood illness. Fever can help our bodies fight infection, and a fever, even a high one, is generally not harmful as long as the underlying reason for the fever is not dangerous, such as a virus. There some instances, however, when we should worry about a child’s fever. Infants less than three months of age with a rectal temperature greater than 100.4 may have a serious illness; parents should call immediately if such a fever is noted so your child can be promptly evaluated. For older infants and children there is no specific temperature that is the sign of a serious problem; instead, our level of concern is guided by a child’s behavior.  Any infant, child or adolescent who is apathetic, inconsolable or looks “toxic” despite adequate doses of fever-reducing medication should be seen and evaluated. If your child can smile and respond to you, and take fluids well, you can treat the fever with fever-reducing medication and observe, but if the fever persists or your child’s behavior or symptoms change, he or she should be seen. If you have any questions about your child’s condition, please do not hesitate to call!

  • Acetaminophen (Tylenol) or ibuprofen (Advil or Motrin) can be used to treat fever.  There is no data to suggest that one is better than another, although some parents feel that their child responds better to one or the other.  Acetaminophen (Tylenol) is safe for young children and is generally our “first line” product to treat fever.  Children must be over six months of age to be given ibuprofen (Advil or Motrin).

    Acetaminophen comes in a rectal suppository form (Feverall) that is useful when a child is vomiting or cannot tolerate oral medication. In these instances, we can advise you about the dose.

  • Since acetaminophen and ibuprofen are different types of medications, it is generally safe to use either one at appropriate dosages and approved intervals. If your child is still “hot” and uncomfortable after an appropriate dose of fever reducing medication, consider a lukewarm bath and pushing fluids for comfort. Neither medication should be used more than four times a day.

  • Yes, as long as the medication you are using does not also contain acetaminophen or ibuprofen in it. Remember to read all medicine labels carefully.

  • If you are using infant drops, use only the dropper that came with the package. If you are using children’s suspension, use the dosage cup that came with the package or a specific medication syringe that can be provided by a pharmacist. Please note that kitchen teaspoons do not accurately measure medication. One pharmacy teaspoon is equal to 5 milliliters (mLs).

 

Acetaminophen (Tylenol) Dosing Information

Give every 4-6 hours, as needed, and not more than five times in 24 hours unless directed by a health care professional.

WeightAgeInfant Oral Suspension: Concentration 5 mL = 160mgChildren’s Suspension 5 mL =160 mgChildren’s Chewables 1 tablet = 160mg
6-11 pounds0-3 months only to be given if directed by a health care professional (see above)
12-17 pounds4-11 months2.5 mL2.5 mL
18-23 pounds12-23 months3.75 mL3.75 mL
24-35 pounds2-3 years5 mL5 mL1 tablets
36-47 pounds4-5 years7.5 mL1.5 tablets
48-59 pounds6-8 years10 mL2 tablets
60-71 pounds9-10 years12.50 mL2.5 tablets
72-95 pounds11 years15 mL3 tablets
 

Ibuprofen (Advil or Motrin) Dosing Information

Give every 6-8 hours, as needed, and not more than four times in 24 hours unless directed by a health care professional.

WeightAgeInfant Drops 1.25 mL = 50 mgChildren’s Liquid 5.0 mL = 100 mgChildren’s Tablets 1 tablet = 50 mgJunior Strength 1 tablet = 100 mg
under 11 poundsless than 6 months
12-17 pounds6-11 months1.25 mL
18-23 pounds12-23 months1.875 mL
24-35 pounds2-3 years5 mL2 tablets
36-47 pounds4-5 years7.5 mL3 tablets
48-59 pounds6-8 years10 mL4 tablets2 tablets
60-71 pounds9-10 years12.5 mL5 tablets2.5 tablets
72-95 pounds11 years6 tablets3 tablets
 

Diphenhydramine (Benadryl)

Diphenhydramine, the active ingredient in Benadryl, is a type of medicine that provides temporary relief of allergy symptoms, including those associated with insect bites and stings. Benadryl comes in a liquid form, chewable form, quick dissolve strips, or as a tablet or capsule. Brand name Benadryl will say “Benadryl Allergy” on the label. Dosage guidelines for diphenhydramine are found in the table below. When comparing the different forms of Benadryl, please remember it is the total milligrams per dose that is the important value.

Benadryl Dosage Chart

Give every 4-6 hours, as needed, and not more than four times in 24 hours unless directed by a health care professional.

WeightBenadryl Liquid 12.5 mg = 5 mLBenadryl Chewable 12.5 mgBenadryl Capsules 25 mgBenadryl Quick Dissolve Strips 25 mg
22-32 pounds3.75 mL
33-43 pounds5 mL1 chewable
44-54 pounds7.5 mL1 1/2 chewable
55-109 pounds10 mL2 chewable1 capsule1 strip
110 pounds and up4 chewable2 capsules2 strips